My patient is medically complex and severely immunocompromised. Does CDC permit any latitude in the COVID-19 vaccination schedule for such patients?

Yes. CDC states that people ages 6 months and older who are moderately or severely immunocompromised have the option to receive 1 additional dose of COVID-19 vaccine at least 2 months following the last recommended 2024–2025 Formula COVID-19 vaccine dose. Further additional dose(s) may be administered, informed by the clinical judgement of the healthcare provider and personal preference and circumstances. Any further additional doses should be administered at least 2 months after the last COVID-19 vaccine dose.