Can Pediarix (DTaP-HepB-IPV) be given to infants born to mothers who are actively infected with hepatitis B (HBsAg-positive)?

Yes, although the package inserts states that Pediarix should only be given to infants born to mothers who are HBsAg-negative, ACIP voted in 2003 to expand its recommendations for use to include infants born to women whose HBsAg status is positive or unknown beginning no earlier than age 6 weeks.