The recommended age for the last dose of HepB in an infant is 6 months. What is the earliest age the last dose can be given to an infant?

The minimum age for the last dose of HepB is age 24 weeks (the minimum age is the youngest age that is acceptable for giving a vaccine and having it “count” as a valid dose.) This allows healthcare providers more flexibility in administering HepB should a parent bring an infant in for a well-baby check before the infant reaches a full 6 months of age. If the third dose is given prior to age 24 weeks the dose should not be counted. Poorer response rates are seen in infants who complete the vaccination series prior to age 24 weeks. The third dose should be repeated when the infant is at least age 24 weeks.