Issue 1,709: August 23, 2023
 
Top Stories
 
Immunize.org Pages and Handouts
 
Featured Resources
 
Notable Publications
 
Global News
 
Upcoming Events
 
Top Stories

New! Immunize.org posts complete suite of materials on vaccination anxiety, designed for healthcare personnel and the public.

Thanks to support from CDC as part of its work to increase vaccine confidence, Immunize.org now offers clinical tools for healthcare professionals and corresponding patient handouts on ways to address vaccination-related anxiety and distress in vaccine recipients of all ages. Together with the materials announced last week for adolescents and adults, the following documents complete Immunize.org’s suite of materials designed to improve the vaccination experience for everyone, especially those who hesitate to accept vaccines because they don’t like injections:

These 1-page resources highlight major principles and include key references. The resources for healthcare personnel are ideal for teaching huddles and short in-service trainings. They may also serve as the basis for quality-improvement efforts.



These resources are ideal to use in concert with Immunize.org’s screening checklists for contraindications to vaccination, which were recently revised to include questions about vaccination anxiety and injection-related fainting.

Related Links
“Effectiveness of Monovalent and Bivalent mRNA Vaccines in Preventing COVID-19–Associated Emergency Department and Urgent Care Encounters among Young Children Aged 6 Months–5 Years—VISION Network, United States, July 2022–June 2023” published in MMWR

CDC published Effectiveness of Monovalent and Bivalent mRNA Vaccines in Preventing COVID-19–Associated Emergency Department and Urgent Care Encounters among Young Children Aged 6 Months–5 Years—VISION Network, United States, July 2022–June 2023 in the August 18 issue of MMWR. A portion of the abstract appears below.

Effectiveness of ≥1 bivalent dose, comparing children with at least a complete primary series and ≥1 bivalent dose to unvaccinated children, irrespective of vaccine manufacturer, was 80% (95% CI = 42%–96%) among children aged 6 months–5 years a median of 58 days (IQR = 32–83 days) after the dose.

Access the MMWR article in HTML or PDF.

Related Link


“Epidemiologic and Clinical Features of Mpox in Adults Aged >50 Years—United States, May 2022–May 2023” published in MMWR

CDC published Epidemiologic and Clinical Features of Mpox in Adults Aged >50 Years—United States, May 2022–May 2023 in the August 18 issue of MMWR. A portion of the summary appears below.

Childhood smallpox vaccination confers some cross-protection against mpox. Although persons aged >50 years likely received childhood smallpox vaccination, they might have more comorbidities and a higher risk for severe mpox compared with those aged ≤50 years. Information about waning cross-protective immunity and how this might affect risk for severe mpox is limited. . . .

Among 29,984 adults with mpox, those aged >50 years had higher prevalences of immunocompromising conditions and HIV and lower prevalence of symptoms than did those aged ≤50 years. Among 1,020 adults aged >50 years with vaccination data, prevalences of pruritus, constitutional symptoms, and hospitalization were lower among those who received JYNNEOS vaccine than among those who had not. . . .


All adults at risk for mpox should receive JYNNEOS vaccine, irrespective of childhood smallpox vaccination status. . . .



Access the MMWR article in HTML or PDF.

Related Link


National Immunization Awareness Month is in full swing; promote vaccination with these helpful resources for all ages

August is National Immunization Awareness Month (NIAM). This annual observance highlights efforts to protect people of all ages against vaccine-preventable diseases through on-time vaccination. This year, NIAM serves as a focal point to get back on track with routine vaccines.

NIAM is a good time to remind healthcare providers that they are still the most trusted source of vaccine information for parents and patients. Encourage patients to schedule appointments to ensure they are up to date on annual exams and recommended vaccines.

CDC’s NIAM web page includes two toolkits, one for reaching healthcare professionals and the other for reaching parents and patients. Each includes key messages, sample social media content, and educational resources. CDC encourages its partners to share these messages and resources throughout August using the hashtag #ivax2protect.

Related Links


“COVID-19 Vaccine Dose for Almost-12-Year-Old?” Watch the 2-minute answer, part of the Ask the Experts Video Series on Facebook, LinkedIn, Twitter, YouTube, and Instagram

Immunize.org’s social media channels make it easy for you to learn a little more every day. This week, our featured episode from the Ask the Experts Video Series is COVID-19 Vaccine Dose for Almost-12-Year-Old? This short clip is available on our YouTube channel, along with our full collection of quick video answers to popular Ask the Experts questions.

Our social media channels feature our most popular printable resources, our Ask the Experts Video Series, and announcements important to frontline vaccinators. Like, follow, and share Immunize.org’s social media accounts. Encourage colleagues and others interested in vaccination to do likewise:


Unity Consortium’s 3Cs program (Confident, Concise, and Consistent) combats vaccine hesitancy

Recognizing the increasing threat to vaccine confidence, Unity Consortium launched a new 3Cs educational program to help healthcare providers deliver strong recommendations for all CDC/ACIP-recommended vaccines for adolescents and young adults.



Pursuit of the 3Cs: Confident, Concise, and Consistent Provider Recommendations for Adolescent Vaccines is a self-guided educational program. It uses video vignettes of healthcare providers responding to common questions from parents and caregivers about whether their adolescent or young adult should receive recommended vaccines. The videos demonstrate how providers can use simple motivational interviewing and shared clinical decision-making strategies to address concerns and move adolescents and parents to be confident in agreeing to vaccination.

Additional elements include a Q&A resource (in English and Spanish), providing sample recommendations by age. The video series includes Spanish captions.

The 3Cs program provides continuing education credit for healthcare providers through Indiana University School of Medicine. Pursuit of the 3Cs video series is funded by Unity’s member organizations and St. Jude Children’s Research Hospital’s HPV Cancer Prevention Program.

Visit Unity’s 3Cs web page for more information and to register for the free, online program.


Spotlight: Immunize.org’s “Handouts” main page provides easy access to hundreds of vaccination-related handouts and fact sheets

Immunize.org's Handouts for Patients and Staff web page leads users to hundreds of vaccination-related patient handouts and fact sheets for healthcare professionals at no charge. All items are ready to print, copy, and distribute widely.

Visit the Handouts for Patients and Staff web page to view more than 230 handouts sorted by:

From the main page, you can search by any of the 22 topics. Some of the most popular are:

The right-hand side of the web page includes links to some of Immunize.org's most popular handouts, including:

You can also view an alphabetical listing of Immunize.org’s more than 230 ready-to-print staff educational materials and patient handouts.

Visit Immunize.org's Handouts for Patients and Staff web page today!


Vaccines in the news

These recent articles convey the potential risks of vaccine-preventable diseases and the importance of vaccination.


Immunize.org Pages and Handouts

Immunize.org's new and updated resources support your work to address vaccination-related anxiety and syncope

With the introduction of the new resources described in today’s top story, Immunize.org now offers a comprehensive suite of new and updated resources to help you improve the vaccination experience of people anxious about injections. Review and share these as you prepare for the busy respiratory virus (influenza, COVID-19, RSV) vaccination season:



Related Links
Immunize.org updates two hepatitis B handouts for healthcare personnel

Immunize.org updated two hepatitis B handouts for healthcare personnel. Edits incorporate CDC's recent recommendation for screening all adults, including healthcare personnel, with a triple-panel test for hepatitis B at least once in a lifetime.



Related Links


Immunize.org updates its handout for healthcare providers, “Vaccines with Diluents: How to Use Them”

Immunize.org updated Vaccines with Diluents: How to Use Them, adding Priorix (MMR, GSK).

Related Links


Featured Resources

Vaccine Track shows largest increase in adult vaccination rates since before the pandemic

Vaccine Track is a website that displays state and national trend data on use of vaccines recommended for U.S. adults. Vaccine Track is produced through a partnership between GSK and Iqvia, a data analytics company.

National vaccination trends in first quarter (Q1) 2023 indicate that vaccination rates are slowly returning to pre-pandemic levels. On average, vaccination reimbursement claims in Q1 2023 are 14% higher than Q1 2019. In Q1 2023, just 11 states were still processing fewer claims for adult vaccinations (excluding influenza) compared to 2019 pre-pandemic levels.

This improvement is likely due, in part, to vaccine-related policy changes in the Inflation Reduction Act of 2022 (IRA). As of January 1, Medicare recipients have no out-of-pocket cost associated with any CDC-recommended Part D vaccines, including routine and travel vaccines. This change lifts a significant barrier to vaccination in Medicare patients. In October 2023, similar Medicaid coverage of all CDC-recommended vaccines with no cost-sharing will go into effect.



Vaccine Track data are refreshed quarterly, while CDC data are typically updated annually. Vaccine Track is the first tool to make comprehensive vaccination claims data across different payer types available publicly.

Related Links


Vaccines.gov enables influenza vaccine search function for the 2023–2024 influenza season

On August 17, the influenza vaccine search functionality on Vaccines.gov, and its Spanish counterpart, Vacunas.gov was activated for the 2023–2024 flu season. Vaccines.gov offers VaccineFinder, a service of Boston Children’s Hospital, to help people find influenza and COVID-19 vaccines for any age group.


Related Links


Immunize.org's elegant "Vaccines Save Lives" black enamel pins make thoughtful tokens of thanks for hard-working colleagues

Immunize.org’s elegantly designed “Vaccines Save Lives” pins are meaningful gifts for people who care about vaccination. The pin makes a refined statement in hard black enamel with gold lettering and edges, measuring 1.125" x 0.75".



The pin features a stick-through-post with the back covered by a round rubber cap that holds the pin securely. A gold metal spring-lock clasp is also provided.

Wear these pins on clothing, uniforms, and white coats to show that you value vaccines.



Click here for "Vaccines Save Lives" pin pricing and ordering information.


Notable Publications

"Disparities in Child and Adolescent COVID-19 Vaccination Coverage and Parental Intent toward Vaccinations for Their Children and Adolescents" published in Annals of Medicine

In the July 14 issue, Annals of Medicine published Disparities in Child and Adolescent COVID-19 Vaccination Coverage and Parental Intent toward Vaccinations for Their Children and Adolescents. A portion of the abstract appears below.

By age group, completed primary series was 13.2% among children <5 years, 43.9% among children 5–11 years, and 63.3% among adolescents 12–17 years. Booster vaccination among those who completed the primary series was 39.1% among children 5–11 years and 55.3% among adolescents 12–17 years. Vaccination coverage differed by race/ethnicity, educational attainment, household income, region, parental COVID-19 vaccination status, prior COVID-19 diagnosis, child’s age group, and parental age group. Parental reluctance was highest for children aged <5 years (46.8%). Main reasons for non-vaccination among reluctant parents were concerns about side effects (53.3%), lack of trust in COVID-19 vaccines (48.7%), and the belief that children do not need a COVID-19 vaccine (38.8%).


Global News

“Progress toward Poliomyelitis Eradication—Pakistan, January 2022–June 2023” published in MMWR and Weekly Epidemiological Record

CDC published Progress toward Poliomyelitis Eradication—Pakistan, January 2022–June 2023 in the August 18 issue of MMWR. On the same day, WHO's Weekly Epidemiological Record published a corresponding article. A portion of the MMWR summary appears below.

Transmission of wild poliovirus type 1 (WPV1) has never been interrupted in Pakistan, one of two countries with ongoing endemic transmission. . . .

Twenty WPV1 cases were reported in Pakistan during 2022, and one case during 2023 (as of June 2023), all clustered within a small geographic area in the southern region of Khyber Pakhtunkhwa province, an area with considerable security challenges and a history of vaccine hesitancy. Recent isolation of WPV1 from sewage in Karachi suggests surveillance gaps and improvements needed in immunization campaign quality. . . .


To interrupt WPV1 circulation, the Pakistan polio program needs to meticulously track and sustain innovative efforts to vaccinate children who are regularly missed during polio vaccination activities, especially in reservoir areas affected by conflict and insecurity. . . .



Access the MMWR article in HTML or PDF.

Related Links


Upcoming Events

Virtual: Today! NCIRD hosts webinar titled “Childhood and Adult Pneumococcal Recommendations” on August 23 at 12:00 p.m. (ET); CE credit offered.

The Immunization Services Division (ISD) in the National Center for Immunization and Respiratory Diseases (NCIRD) will host a webinar in their Current Issues in Immunization Webinar (CIIW) Series titled Childhood and Adult Pneumococcal Recommendations, 12:00–1:00 p.m. (ET) on August 23. During the webinar, Miwako Kobayashi, MD, MPH, Division of Bacterial Diseases, NCIRD, will give updates on childhood and adult pneumococcal recommendations.

Registration is not needed, but participation is limited. CME, CNE, and CPE credit are available.

A recording will be available following the webinar. View archived CIIW videos.

Join the event directly.


Virtual: NCIRD hosts webinar titled "New RSV Vaccines for Adults: General Information and Clinical Guidance" on August 30 at 12:00 p.m. (ET); CE credit offered.

The Immunization Services Division (ISD) in the National Center for Immunization and Respiratory Diseases (NCIRD) will host a webinar in their Current Issues in Immunization Webinar (CIIW) Series titled New RSV Vaccines for Adults: General Information and Clinical Guidance, 12:00–1:00 p.m. (ET) on August 30. During the webinar, Michael Melgar, MD, NCIRD, and Amadea Britton, MD, MPH, NCIRD, will give updates on RSV vaccination recommendations for adults.

Registration is not needed, but participation is limited. CME, CNE, and CPE credit are available.

A recording will be available following the webinar. View archived CIIW videos.

Join the event directly.


For more upcoming events, visit our Calendar of Events.

About IZ Express

IZ Express is supported in part by Grant No. 1NH23IP922654 from CDC’s National Center for Immunization and Respiratory Diseases. Its contents are solely the responsibility of Immunize.org and do not necessarily represent the official views of CDC.

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Editorial Information

  • Editor-in-Chief
    Kelly L. Moore, MD, MPH
  • Managing Editor
    John D. Grabenstein, RPh, PhD
  • Associate Editor
    Sharon G. Humiston, MD, MPH
  • Writer/Publication Coordinator
    Taryn Chapman, MS
    Courtnay Londo, MA
  • Style and Copy Editor
    Marian Deegan, JD
  • Web Edition Managers
    Arkady Shakhnovich
    Jermaine Royes
  • Contributing Writer
    Laurel H. Wood, MPA
  • Technical Reviewer
    Kayla Ohlde

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