- Second unvaccinated child dies of measles in Texas; 607 confirmed measles cases reported in 21 states
- In most of the contiguous United States, the season for administering RSV preventive antibody to infants will resume in October
- Immunize.org updates references in five vaccine standing orders templates for infants, children, and adults
- Immunize.org posts Spanish translations of 17 recently updated VISs
- National Infant Immunization Week is April 21–28; prepare your promotion activities with CDC’s digital media toolkit
- April is National Minority Health Month; one way to support broad access to immunization information is with our translated patient education materials
- Influenza activity continues to decline. This severe season is responsible for the highest hospitalization rate since 2010–11 with at least 580,000 hospitalized so far.
- Watch and share Immunize.org’s Orientation Video Series: Introducing VIS and VIS Translations (mobile view) and learn to navigate our website on your smartphone!
- Vaccines in the news
- NFID releases shareable videos and graphics highlighting the importance of adult vaccines and measles vaccines, along with a dashboard highlighting vaccine uptake at the local level
- Free poster available from Merck with clinical images of childhood measles, mumps, rubella, and chickenpox
- Going fast! Order laminated 2025 U.S. immunization schedule booklets from Immunize.org.
- Updated 65+ Flu Defense website offers resources for healthcare professionals serving older adults
- Help Immunize.org reach more vaccinators through your social media networks. Follow us and share our posts on Facebook, Instagram, and LinkedIn!
- Today. Virtual: Register for Immunize.org Website Office Hours addressing publication archives and vaccine timeline on April 9 at 4:00 p.m. ET or April 10 at 12:00 p.m. ET. Previously recorded sessions available online.
- Virtual: Watch April 15–16 ACIP meeting with discussion of several vaccine recommendations, including MenABCWY, RSV, and chikungunya
- Virtual: Registration open for NFID’s “2025 Annual Conference on Vaccinology Research” on May 5–7; no cost to register, CME credit available
In its April 4 weekly update, CDC reports 607 confirmed measles cases in 2025, with 93% of the cases associated with six outbreaks. Twenty-one states, pictured below, have reported at least one case this year. Most reported cases (481 of 607, 79%) have been reported by the Texas Department of State Health Services. On April 6, media outlets reported that an 8-year-old unvaccinated girl died of measles on April 3 at a Lubbock, Texas, hospital.
A map of 2025 measles cases, as of April 3, is shown below.
Vaccination is the only way to prevent measles: one dose protects about 93% of recipients and a second dose increases the likelihood of protection to 97% or higher. Two doses of MMR are recommended for all children and for adults who lack evidence of immunity and are at increased risk of exposure (such as healthcare professionals and international travelers born in 1957 or more recently) to protect against measles, mumps, and rubella. A single dose of MMR is recommended for previously unvaccinated adults born in 1957 or more recently who lack evidence of immunity and who are not at increased risk of exposure. With the exception of stem cell transplant recipients, people with two documented doses of live measles-containing vaccine administered on or after the first birthday do not need additional MMR doses or blood tests to evaluate measles immunity.
Children routinely receive their first dose of MMR at age 12–15 months and a second dose at 4–6 years, although the second dose may be administered as early as 4 weeks after the first dose. Infants who live in areas experiencing an outbreak or who travel internationally may receive a dose of MMR as early as age 6 months but will still need two doses after their first birthday for full protection. Families should follow state or local public health guidance concerning administration of early doses.
Related Links
- NPR: RFK Jr. Visits Epicenter of Texas Measles Outbreak After Death of Second Child (4/6/25)
- CDC: Measles Cases and Outbreaks main page
- CDC: Public Health Preparedness Checklist: Measles Clusters and Outbreaks (PDF)
- Immunize.org: Vaccines A–Z: Measles main page
- Immunize.org: Standing Orders for Administering Measles, Mumps, and Rubella Vaccine to Children and Teens (PDF)
- Immunize.org: Standing Orders for Administering Measles, Mumps, and Rubella Vaccine to Adults (PDF)
The 2023 ACIP recommendation for nirsevimab (Beyfortus, Sanofi), the RSV preventive antibody for all infants and high-risk toddlers, aligns the recommended timing of Beyfortus administration with the seasonality of RSV infection, which varies across the United States. In most of the “lower 48” states, Beyfortus use should begin October 1 and end March 31. Clinics in these areas with remaining Beyfortus inventory should refrigerate it under proper storage conditions until its recommended use resumes this fall.
Alaska and tropical climates have RSV circulation patterns that differ, and the recommended timing of Beyfortus administration differs. Locations with tropical climates include southern Florida, Hawaii, Guam, Puerto Rico, U.S. Virgin Islands, and U.S.-affiliated Pacific Islands. Providers in these jurisdictions should follow state or territorial guidance on timing of Beyfortus administration.
Related Links
- CDC: Use of Nirsevimab for the Prevention of Respiratory Syncytial Virus Disease Among Infants and Young Children: Recommendations of the Advisory Committee on Immunization Practices — United States, 2023 (8/25/23)
- CDC: Frequently Asked Questions About RSV Immunization with Monoclonal Antibody for Children 19 Months and Younger main page
- American Academy of Pediatrics: Nirsevimab Frequently Asked Questions web page
- Immunize.org: Ask the Experts: Respiratory Syncytial Virus (RSV) web page
Immunize.org updates references in five vaccine standing orders templates for infants, children, and adults
Immunize.org updated the references on five standing orders templates for infants, children, and adults to remove the reference to Appendix B in the Epidemiology and Prevention of Vaccine-Preventable Diseases (the "Pink Book"). The updated standing order templates include:
- Standing Orders for Administering Inactivated Poliovirus Vaccine to Infants and Children
- Standing Orders for Administering Diphtheria, Tetanus, and Acellular Pertussis (DTaP) Vaccine to Children Younger Than Age 7 Years
- Standing Orders for Administering Td/Tdap Vaccine to Adults
- Standing Orders for Administering Tdap/Td Vaccine to Children and Teens Age 7 Years and Older
- Standing Orders for Administering Tdap During Pregnancy
Related Links
- Immunize.org: Clinical Resources: Standing Orders Templates main page
- Immunize.org: Clinical Resources A–Z main page, where you can filter by topic, vaccine, language, or other criteria
Immunize.org updated Spanish translations of 17 VISs to correspond with CDC's recently posted revisions, dated January 31, 2025. The revisions comply with a January 20, 2025, presidential executive order. Changes were limited to replacing the words “persons,” “person,” and “they” with the words "women," "woman," and "she" when referring to pregnancy or breastfeeding.
When given any VIS translation, the patient should also receive the current VIS in English. You Must Provide Patients with Vaccine Information Statements (VISs) – It’s Federal Law! offers additional tips on using VISs.
To locate all available VISs and clinical resources in a given language, visit our translations home page.Check the version dates of your inventory of VIS translations at regular intervals. Discard translations of previous versions as updated translations of current versions become available. Due to minimal content changes and uncertain schedules, Immunize.org elected not to update other VIS translations at this time.
Related Links
- Immunize.org: Vaccine & VISs: Translations main page for access to all translations of VISs
- Immunize.org: QR Code Links to All Vaccine Information Statements (VISs) (PDF)
- Immunize.org: QR Code Links to Vaccine Information Statement (VIS) Translations: Influenza (Flu) Vaccine (Inactivated or Recombinant)
- CDC: Current VISs web page
National Infant Immunization Week (NIIW), April 21–28, highlights the importance of protecting infants from vaccine-preventable diseases and celebrates the achievements of immunization partners. Since 1994, hundreds of communities have joined together during NIIW to highlight the crucial role vaccination plays in protecting our children, communities, and public health.
CDC and the American Academy of Pediatrics recommend that children stay on track with their well-child appointments and routine vaccinations. Completing the recommended vaccinations by age 2 years is the best way to protect young children from 15 potentially life-threatening diseases. In light of the recent measles outbreaks, these messages are more important than ever.
CDC makes it simple to plan your NIIW activities by using their promotional materials including English and Spanish logos, sample social media content, social graphics, and key messages. Please share your posts using the hashtag #ivax2protect. Find more actionable strategies, resources, and data to support getting people of all ages on-schedule with their routine immunizations.
Related Links
- CDC: National Infant Immunization Week (NIIW) main page
- CDC: Promotional Materials main page
- CDC: Routine Immunizations on Schedule for Everyone (RISE) main page
- Immunize.org: Parent Handouts main page
April is National Minority Health Month, a time to focus on the importance of achieving health for all. Millions of Americans face persistent barriers to preventive services, including immunization.
One way Immunize.org works to reduce barriers for people whose preferred language is not English is to make available translations of VISs as well as some of our most popular vaccination-related handouts and fact sheets. Visit our Translations main page to access all translated resources.
Related Links
- National Minority Quality Forum (NMQF): National Minority Health Month web page
- NMQF: NMQF Announces 2025 National Minority Health Month Theme: “Health Unlocked: Access, Alignment, Action” (4/3/25)
- Immunize.org: Translations main page, where you can locate available translations of clinical resources and VISs, organized by language
For week 13, ending March 29, CDC’s Weekly Influenza Surveillance Report, FluView, only 14 jurisdictions showed influenza-like illness activity at moderate to high levels. CDC classified this season as a high-severity season for people of all ages, with the highest hospitalization rate recorded since the 2010–11 season. During week 13, 3.2% of outpatient visits were for influenza-like illness, remaining above the epidemic threshold of 3.0% for the eighteenth consecutive week. Nine pediatric deaths associated with seasonal influenza virus infection were reported during week 13, bringing the 2024–25 season total to 168 childhood deaths.
RESP-NET
Visit the CDC Respiratory Virus Hospitalization Surveillance Network (RESP-NET) for weekly reports of hospitalizations due to three vaccine-preventable seasonal respiratory viruses: COVID-19, influenza, and RSV.
Influenza Vaccination Dashboard
CDC's Weekly Flu Vaccination Dashboard shows the latest seasonal coverage statistics.
CDC recommends everyone age 6 months and older get annual influenza vaccination. Vaccination remains important for all eligible, unvaccinated people, as long as influenza is circulating.
Identify pharmacies in your area that may offer influenza and COVID-19 vaccines by entering a zip code in the VaccineFinder on Vaccines.gov or Vacunas.gov.
Related Links
- CDC: Weekly National Flu Vaccination Dashboard main page
- CDC: FluView main page
- CDC: RESP-NET main page
- Immunize.org: Vaccines A–Z: Influenza main page
Learn how to navigate Immunize.org’s VISs and VIS translations on your smartphone. Check out the “mobile view” version of our 4-minute Orientation Video Series: Introducing VIS and VIS Translations.
Available on our YouTube channel, this is part of our Orientation Video Series.
Share these videos with anyone who would like to learn more about Immunize.org’s website to support effective immunization practices.
- Immunize.org: Webinars & Videos Orientation Video Series page
- Facebook at ImmunizeOrg
- Instagram at ImmunizeOrg
- LinkedIn at ImmunizeOrg
- YouTube at ImmunizeOrg
These recent articles convey the potential risks of vaccine-preventable diseases and the importance of vaccination.
- New York Times: Judge Blocks H.H.S. from Terminating $11 Billion in Public Health Grants (4/3/25)
- New York Times: Shingles Vaccine Can Decrease Risk of Dementia, Study Finds (4/2/25)
- NBC: Dozens of Free Measles Vaccine Clinics Close in Texas as Federal Funding Is Cut (4/1/25)
Immunize.org overhauled a popular vaccine storage resource. The Vaccine Storage Quick Reference (formerly entitled “Vaccine Handling Tips”) is a 1-page guide to appropriate storage temperatures for vaccines approved or authorized for routine use in the United States. Vaccines exclusively used for international travel are not included. Consider placing a copy on each vaccine storage unit today.
Key updates include:
- Clear storage information: vaccines are now shown within color-coded boxes based on storage in a refrigerator, freezer, or ultra-cold freezer
- Vaccine listings: vaccines are listed by disease name only except when storage requirements apply only to specified brands
- Improved readability: the font size was enlarged
- Additional resources: links lead to other relevant resources from Immunize.org and CDC that guide vaccine storage and response to improper temperature exposure
- Special cases: a separate box provides details for vaccines that are routinely frozen but may be refrigerated for a limited time
- Vaccine diluents: information on proper storage of vaccine diluents is included
NFID.org recently released new resources in its NFID Resource Library to help increase adult vaccination rates across the United States.
New! Shareable Videos:
- One Thing We Can Agree On (30 seconds)
- Preventable Problems (30 seconds)
- Do Your Part (15 seconds)
NFID also launched the U.S. Vaccine Uptake Dashboard, a pilot tool designed to provide local insights to help public health leaders develop effective, community-specific vaccination campaigns. Developed in collaboration with the Association of Immunization Managers (AIM), the National Association of County and City Health Officials (NACCHO), and Fraym, the NFID dashboard empowers stakeholders to allocate resources where they are most needed. Healthcare professionals may request access to the dashboard.
Previously announced measles resources from NFID include:
- Frequently Asked Questions About Measles (updated based on common questions about current outbreaks)
- Measles Awareness: Sample Social Media Posts and Graphics
- Contagious Chronicles: Measles Alert (consumer-friendly audio recording)
- Combating the Resurgence of Measles and Other Preventable Diseases (on-demand webinar for healthcare professionals)
- Shareable Videos:
- 5 Things You Need to Know About Measles in 30 Seconds (30 seconds)
- This Is How Easy It Is to Spread Measles (15 seconds)
- Measles . . . Don’t Come Back (17 seconds)
- Infographics:
Share widely to help combat misinformation and promote measles vaccination.
In light of the ongoing measles outbreaks in the United States, Merck recently posted an updated PDF copy of its longstanding poster titled A Guide To Differential Diagnosis: Selected Rash/Illness In Children. The 3-panel graphic provides images and text descriptions to help differentiate the rashes and other clinical manifestations of measles, mumps, rubella, and chickenpox (varicella).
There are two widely available and interchangeable vaccines against measles, mumps, and rubella in the United States: MMR-II (Merck) and Priorix (GSK). Merck is the only manufacturer of vaccines to prevent chickenpox (varicella) in the United States.
Laminated booklets of the 2025 U.S. child and adolescent immunization schedule and the 2025 U.S. adult immunization schedule are available now in the Immunize.org shop.
The schedules are available online as PDFs from CDC at no cost. Immunize.org’s laminated booklets are ideal for use in any busy healthcare setting where vaccines are given. Features include:
- Durability: Their tough coating can be wiped down, and they can stand up to a year's worth of use.
- Format: Each schedule is produced in an 8.5” X 11” booklet format; with color coding for easy reading, our laminated schedules replicate the original CDC formatting, including all tables and notes. The adult schedule is 16 pages and the child and adolescent schedule is 20 pages.
- Easy access to CDC updates: The CDC online schedule includes an addendum page that will display ACIP’s new recommendations as CDC adopts them during 2025. Each Immunize.org laminated schedule addendum page includes QR codes you can scan to view or print the online addendum page as it is revised.
- Bonus content: Both schedules include a bonus page with Immunize.org’s popular 1-page handout summarizing the dose, route, and needle size recommendations for all vaccines and recipients.
Pricing:
| Child and Adolescent Booklets | Adult Booklets | |
| 1 copy: $10.50 | 1 copy: $10.00 | |
| 2–4 copies: $10.00 each | 2–4 copies: $9.50 each | |
| 5–19 copies: $9.00 each | 5–19 copies: $8.50 each | |
| 20–99 copies: $8.00 each | 20–99 copies: $7.50 each | |
| 100–499 copies: $6.50 each | 100–499 copies: $6.00 each | |
| 500–999 copies: $5.50 each | 500–999 copies: $5.00 each | |
| 1,000–1,999 copies: $4.50 each | 1,000–1,999 copies: $4.00 each | |
| 2,000+ copies: $3.75 each | 2,000+ copies: $3.25 each | |
For additional information, call 651-647-9009 or email admininfo@immunize.org.
Related Links
- Immunize.org: Laminated Child and Adolescent Immunization Schedules (0–18 years) web page
- Immunize.org: Laminated Adult Immunization Schedules (19 and older) web page
- Immunize.org: Shop Immunize.org main page
Confident healthcare provider recommendations for influenza vaccine are powerfully persuasive. This influenza season has been a tough one and it is not over yet. To help you maximize patient protection, Immunize.org, in collaboration with CSL Seqirus, updated the 65+ Flu Defense website.
This helpful site includes information, tools, and tips for communicating with adults age 65 and older about the scope and severity of influenza. Resources include:
- Influenza in Adults 65+: The Facts
- Influenza Vaccination: Questions Patients Aged 65 and Older Frequently Ask Their HCP
- The Importance of Preventing Influenza and COVID-19
Older adults are at increased risk of severe influenza, COVID-19, and RSV illness, including hospitalization and death, especially if they are not up to date on these vaccinations. A clinician recommendation is the most important reason why a patient will get vaccinated.
Check out the updated 65+ Flu Defense website to assist your ongoing efforts in protecting this vulnerable population.
Immunize.org offers a social media program to highlight our educational resources for a new audience of vaccinators. Our social media channels feature our most popular printable resources and Ask the Experts questions, as well as announcements important to frontline vaccinators. Our short educational videos are all available on our YouTube channel in the Ask the Experts Video Series.
Like, follow, and share Immunize.org’s social media accounts and encourage colleagues and others interested in vaccination to do likewise:
- Facebook at ImmunizeOrg
- Instagram at ImmunizeOrg
- LinkedIn at Immunize.org
- YouTube at ImmunizeOrg
To learn simple tips and tricks for using our website efficiently, please register for our next set of Website Office Hours on Wednesday, April 9 at 4:00 p.m. (ET) or Thursday, April 10 at 12:00 p.m. (ET). The same content will be covered in both sessions.
We will open each 45-minute session with a short, live demonstration on navigating the following site content: publication archives, vaccine timeline, and about us. You can submit questions when you register or live on Zoom during the session.
Register today for Immunize.org Website Office Hours (content is the same for both):
Mark your calendar for future Immunize.org Website Office Hours.
CDC will convene the ACIP on April 15–16. The ACIP will discuss vaccines targeting chikungunya, COVID-19, cytomegalovirus, HPV, influenza, Lyme disease, meningococcal disease, mpox, pneumococcal disease, and RSV. An update on the multistate measles outbreak will be presented.
No registration is required to watch webcasts of live ACIP meetings or listen via telephone. Opportunities for written or oral public comment are described on the website.
View the agenda and anticipated vote language.
Related Links
- CDC: ACIP main page for access to webcast, agendas
- CDC: ACIP: Meeting Information for presentation slides, content from previous meetings, and information about future meetings
The National Foundation for Infectious Diseases (NFID) transitioned the format of its 2025 Annual Conference on Vaccinology Research on May 5–7 to an online, virtual format and opened up registration at no cost. The conference brings together disciplines involved in vaccine research, development, implementation, and real-world evaluation. The theme of the 2025 conference is "Vaccines for a Resilient Future: Innovation and Impact" and the program is designed to facilitate the exchange of ideas internationally across a broad range of disciplines, addressing challenges and breakthroughs in vaccinology.
Registration is now open. There is no cost to register.
NFID will offer up to 9.5 hours of CE and CME for the live online activity.